Bioinformatics with protein sequence: Difference between revisions
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#link to [http://www.uniprot.org Uniprot page] for each target protein | #link to [http://www.uniprot.org Uniprot page] for each target protein | ||
#[http://www.nesg.org/PXS Pxs] to predict protein crystallography success | #[http://www.nesg.org/PXS Pxs] to predict protein crystallography success | ||
#predict signal peptide with signalp | |||
#[http://www-nmr.cabm.rutgers.edu/bioinformatics/disorder DisMeta] - disorder and secondary structure prediction <ref>Rossi, P. et. al. (2009). "A microscale protein NMR sample screening pipeline." ''J. Biomol. NMR'', '''in press.</ref> | #[http://www-nmr.cabm.rutgers.edu/bioinformatics/disorder DisMeta] - disorder and secondary structure prediction <ref>Rossi, P. et. al. (2009). "A microscale protein NMR sample screening pipeline." ''J. Biomol. NMR'', '''in press.</ref> | ||
#prof predictionof secondary structure | #prof predictionof secondary structure | ||
Revision as of 22:31, 12 November 2009
SPINE database software
SPINE (Structural Proteomics in the NorthEast) is the NESG's project coordination database.
The SPINE data model closely mirrors the current pepcDB data model with database tables responsible for tracking target, construct, expression, purification, X-Ray and NMR structure data. Spine generates weekly targetDB and pepcDB data depositions which are retrieved by the PSI-KB, generates meta-data required for archiving NESG constructs at the PSI-MR, and provides key NESG protein production pipeline, sample distribution, and structure determination statistics.
SPINE's Protein Sample Tube (PST) records provide detais about NESG protein samples and link into the samples target, construct, expression, purification, and structure screening SPINE records.
SPINE provides Bioinformatics information based on the protein sequences, including:
- link to Uniprot page for each target protein
- Pxs to predict protein crystallography success
- predict signal peptide with signalp
- DisMeta - disorder and secondary structure prediction [1]
- prof predictionof secondary structure
- ZincFinder
- Competition report
Web based servers for sequence analysis:
- PredictProtein
PredictProtein is a service for sequence analysis, structure and function prediction. When you submit any protein sequence PredictProtein retrieves similar sequences in the database and predicts aspects of protein structure and function. You may want to save the Predictprotein results on the local disk, because after a few days they will delete the files from their data base. Registration is free.
- ExPASy Proteomics Server
The ExPASy (Expert Protein Analysis System) proteomics server of the Swiss Institute of Bioinformatics (SIB) is dedicated to the analysis of protein sequences and structures.
- Pfam database
The Pfam database is a large collection of protein families and hidden Markov models. For each family you can:- Look at multiple alignments.
- View protein domain architectures.
- Examine species distribution.
- Follow links to other databases.
- View known protein structures.
References
- ↑ Rossi, P. et. al. (2009). "A microscale protein NMR sample screening pipeline." J. Biomol. NMR, in press.