Bioinformatics with protein sequence

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Revision as of 21:44, 12 November 2009 by TheresaRamelot (talk | contribs)
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SPINE database software

SPINE (Structural Proteomics in the NorthEast) is the NESG's project coordination database.
The SPINE data model closely mirrors the current pepcDB data model with database tables responsible for tracking target, construct, expression, purification, X-Ray and NMR structure data. Spine generates weekly targetDB and pepcDB data depositions which are retrieved by the PSI-KB, generates meta-data required for archiving NESG constructs at the PSI-MR, and provides key NESG protein production pipeline, sample distribution, and structure determination statistics.


SPINE's Protein Sample Tube (PST) records provide detais about NESG protein samples and link into the samples target, construct, expression, purification, and structure screening SPINE records.


SPINE provides Bioinformatics information based on the protein sequences, including:

  1. link to [| Swiss-Prot/Uniprot page] for each target protein
  2. Competition report
  3. ZincFinder
  4. pXs to predict protein crystallography success
  5. DisMeta - disorder and secondary structure prediction