View source for SPINS

== '''Introduction'''  ==

SPINS (Standardizing Protein NMR&nbsp;Storage) is an object oriented relational database used in the Montelione group for high-throughput NMR&nbsp;data storage, analysis and submission [http://www.ncbi.nlm.nih.gov/pubmed/16395675?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=4 [1]].

== '''Uses'''  ==

SPINS features useful tools for archiving of FIDs for structure determination projects.&nbsp; Furthermore, the exact pulse sequence experiments used in the data collection are captured by SPINS. 

SPINS also has a tool for submission of time domain NMR data for a structure project to BMRB under a given BMRB&nbsp;ID. 

== '''SPINS&nbsp;Interface'''  ==

The main page of the SPINS interface is shown in Figure 1.&nbsp; The main page features several functions including, input of NMR data, inserting NMR pulse sequences, and a project manage.&nbsp;&nbsp; Clicking the "help" link provides a complete manual in pdf format. 

==== Figure 1:&nbsp; SPINS interface  ====

[[Image:SPINS mainpage.png|600x450px]] 

Common functions used in creating and managing structure determination projects include the multiple FID insert tool (Figure 2), the project manager (Figure 3) and the tools page which includes a function for transmitting NMR data in a SPINS project to the BMRB (Figure 4). 

==== Figure 2:&nbsp; FID insert tool<br>  ====

[[Image:SPINS insertpage.png|600x300px]] 

==== Figure 3:&nbsp; Project Manager<br>  ====

[[Image:SPINS projectpage.png|600x400px]] 

==== Figure 4:&nbsp; BMRB&nbsp;tool  ====

[[Image:SPINS toolspage.png|600x320px]] 

<br> 

== '''References'''  ==

[http://www.ncbi.nlm.nih.gov/pubmed/16395675?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=4 1. Baran, M., Moseley, H.N.B., Aramini, J.M., Bayro, M.J., Monleon, D., Locke, J. and Montelione, G.T. (2006) SPINS: A laboratory information management system for organizing and archiving intermediate and final results from NMR protein structure determination.&nbsp; ''PROTEINS 62'', 843 – 851.]&nbsp; 

<br> 

--JimAramini- 03 Nov 2009