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As part of the NIH funded PSI-2 project, the NESG dedicates 70%&nbsp;of its resources to the determination of targeted families assigned by the [http://psi-big4.org PSI&nbsp;BIG&nbsp;group], <br>30% to targets nominated by the <meta content="text/html; charset=utf-8" http-equiv="Content-Type"></meta><meta content="Word.Document" name="ProgId"></meta><meta content="Microsoft Word 11" name="Generator"></meta><meta content="Microsoft Word 11" name="Originator"></meta><link href="file:///C:\Users\kellere\AppData\Local\Temp\msohtml1\01\clip_filelist.xml" rel="File-List"></link><!--[if gte mso 9]><xml>
<br>As part of the NIH funded PSI-2 project, the NESG dedicates 70% of its resources to the determination of targeted families selected by the [http://psi-big4.org PSI BIG], 30% to targets nominated by the academic community and 30% to its own biomedically oriented projects such as key proteins in [http://nesg.org:9090/HCPIN/index.jsp Human cancer interaction networks] and bacterial lipoproteins.  
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<![endif]--><span style="font-size: 12pt; font-family: &quot;Times New Roman";">academic</span> community and 30%&nbsp;to its own <meta content="text/html; charset=utf-8" http-equiv="Content-Type"></meta><meta content="Word.Document" name="ProgId"></meta><meta content="Microsoft Word 11" name="Generator"></meta><meta content="Microsoft Word 11" name="Originator"></meta><link href="file:///C:\Users\kellere\AppData\Local\Temp\msohtml1\01\clip_filelist.xml" rel="File-List"></link><!--[if gte mso 9]><xml>
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<![endif]--><span style="font-size: 12pt; font-family: &quot;Times New Roman";">biomedicaly</span> oriented projects such as key proteins in Human cancer interaction<br>networks and bacterial lipoproteins.  


Throughout PSI-2, protein families proposed by the PSI&nbsp;BIG&nbsp;group have been selected by the PSI-2 large scale centers via a lottery system overseen by the <br>PSI&nbsp;BIG&nbsp;group.&nbsp; Members of protein families selected by the BIG&nbsp;group are studied by the large scale centers prior to family selection and each center proposes<br>families that they wish to pursue.&nbsp; The PSI&nbsp;BIG&nbsp;group <meta content="text/html; charset=utf-8" http-equiv="Content-Type"></meta><meta content="Word.Document" name="ProgId"></meta><meta content="Microsoft Word 11" name="Generator"></meta><meta content="Microsoft Word 11" name="Originator"></meta><link href="file:///C:\Users\kellere\AppData\Local\Temp\msohtml1\01\clip_filelist.xml" rel="File-List"></link><!--[if gte mso 9]><xml>
Throughout PSI-2, protein families proposed by the PSI BIG group have been selected by the PSI-2 large scale centers via a lottery system overseen by the PSI BIG group. Members of protein families selected by the BIG group are studied by the large scale centers prior to family selection and each center proposes families that they wish to pursue. The PSI BIG group resolves conflicts where more than one large scale center proposes to study the same protein family.  
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<![endif]--><span style="font-size: 12pt; font-family: &quot;Times New Roman";">resolves</span> conflicts where more than one large scale center <meta content="text/html; charset=utf-8" http-equiv="Content-Type"></meta><meta content="Word.Document" name="ProgId"></meta><meta content="Microsoft Word 11" name="Generator"></meta><meta content="Microsoft Word 11" name="Originator"></meta><link href="file:///C:\Users\kellere\AppData\Local\Temp\msohtml1\01\clip_filelist.xml" rel="File-List"></link><!--[if gte mso 9]><xml>
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<![endif]--><span style="font-size: 12pt; font-family: &quot;Times New Roman";">proposes</span> the same protein family.  


Before selecting a protein family, the NESG evaluates family members with a number of <meta content="text/html; charset=utf-8" http-equiv="Content-Type"></meta><meta content="Word.Document" name="ProgId"></meta><meta content="Microsoft Word 11" name="Generator"></meta><meta content="Microsoft Word 11" name="Originator"></meta><link href="file:///C:\Users\kellere\AppData\Local\Temp\msohtml1\01\clip_filelist.xml" rel="File-List"></link><!--[if gte mso 9]><xml>
Before selecting a protein family, the NESG evaluates family members with a number of predictors:  
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<![endif]--><span style="font-size: 12pt; font-family: &quot;Times New Roman";">predictors</span>:  


*[http://nmr.cabm.rutgers.edu:8080/PXS/calculatePXS.jsp Pxs]  
*[http://nmr.cabm.rutgers.edu:8080/PXS/calculatePXS.jsp Pxs]  
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<br>  
<br>  


Result of PSI-2 protein family drafts:  
Results of PSI-2 protein family drafts:  


*[http://psi-big4.org/target/draft_2005-10/ Draft pick of 1369 Pfam families (Oct 2005)]  
*[http://psi-big4.org/target/draft_2005-10/ Draft pick of 1369 Pfam families (Oct 2005)]  
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*[http://psi-big4.org/target/small_mega_2007-06/ Selection of 4 small MEGA families (June 2007)]  
*[http://psi-big4.org/target/small_mega_2007-06/ Selection of 4 small MEGA families (June 2007)]  
*[http://psi-big4.org/target/midsize_mega_2007-12/ Draft selection of 4 mid size MEGA families (Dec 2007)<br>]  
*[http://psi-big4.org/target/midsize_mega_2007-12/ Draft selection of 4 mid size MEGA families (Dec 2007)<br>]  
*[http://psi-big4.org/target/midsize_mega_2007-12/][http://psi-big4.org/target/super_mega_2007-12/3.40.50.720/ Draft pick of NAD(P)-binding Rossmann domain (Dec 2007)]  
*[http://psi-big4.org/target/super_mega_2007-12/3.40.50.720/ Draft pick of NAD(P)-binding Rossmann domain (Dec 2007)]  
*[http://psi-big4.org/target/super_mega_2007-12/3.20.20.70/ Draft pick of Aldolase Class I (Dec 2007)]  
*[http://psi-big4.org/target/super_mega_2007-12/3.20.20.70/ Draft pick of Aldolase Class I (Dec 2007)]  
*[http://psi-big4.org/target/super_mega_2007-12/3.40.50.150/ Draft pick of VP39 (Dec 2007)]  
*[http://psi-big4.org/target/super_mega_2007-12/3.40.50.150/ Draft pick of VP39 (Dec 2007)]  

Latest revision as of 22:30, 10 December 2009


As part of the NIH funded PSI-2 project, the NESG dedicates 70% of its resources to the determination of targeted families selected by the PSI BIG, 30% to targets nominated by the academic community and 30% to its own biomedically oriented projects such as key proteins in Human cancer interaction networks and bacterial lipoproteins.

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Before selecting a protein family, the NESG evaluates family members with a number of predictors:


Results of PSI-2 protein family drafts:

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